Title : Phytoestrogens modulate binding response of estrogen receptors alpha and beta to the estrogen response element.

Pub. Date : 2003 Dec 17

PMID : 14664520






2 Functional Relationships(s)
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1 Here, we investigated the effects of some dietary phytoestrogens such as the isoflavones genistein and daidzein, its metabolite equol, and the coumestane coumestrol on the binding rate of ERalpha and ERbeta to ERE by a nonradioactive real-time method, the Biacore Technology. daidzein estrogen receptor 1 Homo sapiens
2 The endogenous hormone 17beta-estradiol as well as coumestrol and daidzein metabolite equol activate the binding of ERbeta to ERE only slightly more effectively than the binding of ERalpha to ERE. daidzein estrogen receptor 1 Homo sapiens