Title : The use of zebrafish mutants to identify secondary target effects of acetylcholine esterase inhibitors.

Pub. Date : 2004 Feb

PMID : 14657522






2 Functional Relationships(s)
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1 By application of simple assays and comparison with the phenotype of embryos with genetic lesions in the ache gene, we demonstrate that only one of the AChE inhibitors (galanthamine) reproduces the phenotype of ache mutant embryos. Galantamine acetylcholinesterase Danio rerio
2 By application of simple assays and comparison with the phenotype of embryos with genetic lesions in the ache gene, we demonstrate that only one of the AChE inhibitors (galanthamine) reproduces the phenotype of ache mutant embryos. Galantamine acetylcholinesterase Danio rerio