Title : N-tritylprolinal: an efficient building block for the stereoselective synthesis of proline-derived amino alcohols.

Pub. Date : 2003 Dec 12

PMID : 14656102






1 Functional Relationships(s)
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1 N-Tritylprolinal (prepared in four steps from l-proline) shows a very high Felkin diastereoselectivity in its reaction with various nucleophiles, leading to a straightforward and highly stereoselective access to syn-proline-derived amino alcohols. Proline synemin Homo sapiens