Title : Advanced glycation end product ligands for the receptor for advanced glycation end products: biochemical characterization and formation kinetics.

Pub. Date : 2004 Jan 1

PMID : 14654047






2 Functional Relationships(s)
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1 Ribose-AGEs bound RAGE with high affinity within 1 week of incubation in contrast to glucose- and fructose-AGE, which required 12 and 6 weeks, respectively, to generate equivalent RAGE ligands (IC50=0.66, 0.93, and 1.7 microM, respectively). Ribose advanced glycosylation end-product specific receptor Homo sapiens
2 Ribose-AGEs bound RAGE with high affinity within 1 week of incubation in contrast to glucose- and fructose-AGE, which required 12 and 6 weeks, respectively, to generate equivalent RAGE ligands (IC50=0.66, 0.93, and 1.7 microM, respectively). Ribose advanced glycosylation end-product specific receptor Homo sapiens