Title : Role of the epidermal growth factor receptor in signaling strain-dependent activation of the brain natriuretic peptide gene.

Pub. Date : 2004 Mar 5

PMID : 14645255






1 Functional Relationships(s)
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1 The metalloproteinase inhibitor, GM-6001, prevented the induction of HBEGF ectoshedding and the hBNP promoter response to strain, suggesting a critical role for the metalloproteinase-dependent cleavage event in signaling the strain response. N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide heparin binding EGF like growth factor Homo sapiens