Title : Identification of a binding site on human FGF-2 for fibrinogen.

Pub. Date : 2004 Mar 15

PMID : 14630795






1 Functional Relationships(s)
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1 Exchange of 5 residues (Phe95, Ser100, Asn102, Arg107, and Arg109) from FGF-2 into the corresponding sites in the third cassette of FGF-1 imparted high-affinity binding with apparent dissociation constants (Kd) of 5.3 nM and 8.6 nM, respectively, compared with 1.3 nM for wild-type FGF-2. ZP120 fibroblast growth factor 2 Homo sapiens