Pub. Date : 2004 Feb 13
PMID : 14625298
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CAPE activated Fas by a Fas ligand (Fas-L)-independent mechanism, induced p53-regulated Bax protein, and activated caspases. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |
| 2 | SB203580, a specific inhibitor of p38 MAPK, partially suppressed CAPE-induced p53 activation, Bax expression, and apoptosis, consistent with a mechanism by which CAPE leads to Bax activation, known to be regulated by p38 and p53. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |
| 3 | SB203580, a specific inhibitor of p38 MAPK, partially suppressed CAPE-induced p53 activation, Bax expression, and apoptosis, consistent with a mechanism by which CAPE leads to Bax activation, known to be regulated by p38 and p53. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |
| 4 | SB203580, a specific inhibitor of p38 MAPK, partially suppressed CAPE-induced p53 activation, Bax expression, and apoptosis, consistent with a mechanism by which CAPE leads to Bax activation, known to be regulated by p38 and p53. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |