Pub. Date : 2003 Dec 19
PMID : 14623033
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prostaglandin E2 aggravates gastric mucosal injury induced by histamine in rats through EP1 receptors. | Dinoprostone | prostaglandin E receptor 1 | Rattus norvegicus |
| 2 | The mucosal ulcerogenic and vascular permeability responses induced by histamine plus PGE2 were both suppressed by pretreatment with ONO-AE829, the EP1 antagonist. | Dinoprostone | prostaglandin E receptor 1 | Rattus norvegicus |
| 3 | This action of PGE2 is mediated by EP1 receptors and functionally associated with potentiation of the increased vascular permeability caused by histamine through stimulation of H1-receptors. | Dinoprostone | prostaglandin E receptor 1 | Rattus norvegicus |