Pub. Date : 2003 Oct
PMID : 14619570
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | OBJECTIVE: To explore the effects of arsenic trioxide (As2O3) on tissue factor (TF), plasminogen activator inhibitor-1(PAI-I) and PAI-2 expression in NB4, HL-60 and THP-1 cells. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
2 | OBJECTIVE: To explore the effects of arsenic trioxide (As2O3) on tissue factor (TF), plasminogen activator inhibitor-1(PAI-I) and PAI-2 expression in NB4, HL-60 and THP-1 cells. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
3 | OBJECTIVE: To explore the effects of arsenic trioxide (As2O3) on tissue factor (TF), plasminogen activator inhibitor-1(PAI-I) and PAI-2 expression in NB4, HL-60 and THP-1 cells. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
4 | The TF antigen levels were down-regulated during the As2O3-induced apoptosis of NB4 cells (P < 0.01), and the down-regulation effect of TF antigen levels was in the As2O3-concentration dependent fashion. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
5 | The TF antigen levels were down-regulated during the As2O3-induced apoptosis of NB4 cells (P < 0.01), and the down-regulation effect of TF antigen levels was in the As2O3-concentration dependent fashion. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
6 | The TF antigen levels were up-regulated and the PAI-2 antigen levels were down-regulated during the As2O3-induced apoptosis of HL-60 cells (P < 0.01 and P < 0.05, TF and PAI-2 respectively). | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
7 | The TF antigen levels were up-regulated and the PAI-2 antigen levels were down-regulated during the As2O3-induced apoptosis of HL-60 cells (P < 0.01 and P < 0.05, TF and PAI-2 respectively). | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
8 | The TF and PAI-2 antigen levels in THP-1 cells were up-regulated after the exposure to 8 mumol/L As2O3 for 24 h (P < 0.05 and P < 0.01, TF and PAI-2 respectively). | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
9 | The TF and PAI-2 antigen levels in THP-1 cells were up-regulated after the exposure to 8 mumol/L As2O3 for 24 h (P < 0.05 and P < 0.01, TF and PAI-2 respectively). | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |
10 | CONCLUSION: The effects of As2O3 on TF, PAI-1 and PAI-2 antigen levels in NB4, HL-60 and THP-1 cells are distinct. | Arsenic Trioxide | coagulation factor III, tissue factor | Homo sapiens |