Title : Angiotensin-converting enzyme is involved in outside-in signaling in endothelial cells.

Pub. Date : 2004 Jan 9

PMID : 14615289






4 Functional Relationships(s)
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1 The ACE inhibitors ramiprilat and perindoprilat, and the substrate bradykinin (but not angiotensin I), enhanced the activity of ACE-associated CK2 and the phosphorylation of ACE Ser1270 in cultured endothelial cells. ramiprilat angiotensin I converting enzyme Homo sapiens
2 The ACE inhibitors ramiprilat and perindoprilat, and the substrate bradykinin (but not angiotensin I), enhanced the activity of ACE-associated CK2 and the phosphorylation of ACE Ser1270 in cultured endothelial cells. ramiprilat angiotensin I converting enzyme Homo sapiens
3 The ACE inhibitors ramiprilat and perindoprilat, and the substrate bradykinin (but not angiotensin I), enhanced the activity of ACE-associated CK2 and the phosphorylation of ACE Ser1270 in cultured endothelial cells. ramiprilat angiotensin I converting enzyme Homo sapiens
4 Prolonged ramiprilat treatment increased ACE expression in primary cultures of human endothelial cells and in vivo (mouse lung), a response that was prevented by pretreatment with the JNK inhibitor SP600125. ramiprilat angiotensin I converting enzyme Homo sapiens