Title : Prolactin dysregulation in women with subclinical hypothyroidism: effect of levothyroxine replacement therapy.

Pub. Date : 2003 Oct

PMID : 14611708






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1 This study investigated the effect of levothyroxine treatment on serum prolactin (PRL) levels in women with subclinical hypothyroidism. Thyroxine prolactin Homo sapiens
2 This study investigated the effect of levothyroxine treatment on serum prolactin (PRL) levels in women with subclinical hypothyroidism. Thyroxine prolactin Homo sapiens
3 In the levothyroxine group (n = 31) basal and peak PRL levels were significantly reduced after 24 and 48 weeks (p = 0.03 and p = 0.001). Thyroxine prolactin Homo sapiens
4 Based on this double-blinded, placebo-controlled study we demonstrate that in subclinical hypothyroidism PRL regulation is altered with elevated basal and stimulated PRL levels, and that physiologic levothyroxine treatment restores PRL concentrations. Thyroxine prolactin Homo sapiens
5 Based on this double-blinded, placebo-controlled study we demonstrate that in subclinical hypothyroidism PRL regulation is altered with elevated basal and stimulated PRL levels, and that physiologic levothyroxine treatment restores PRL concentrations. Thyroxine prolactin Homo sapiens