Title : Phosphatidylethanolamine-N-methyltransferase activity and dietary choline regulate liver-plasma lipid flux and essential fatty acid metabolism in mice.

Pub. Date : 2003 Nov

PMID : 14608048






1 Functional Relationships(s)
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1 Mice with a homozygous disruption of the PEMT gene are dependent on the 1,2-diacylglycerol cholinephosphotransferase (CDP-choline) pathway for the synthesis of PC and develop severe liver steatosis when fed a diet deficient in choline. Phosphatidylcholines cut-like homeobox 1 Mus musculus