Title : Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor.

Pub. Date : 2004 Jan

PMID : 14593076






1 Functional Relationships(s)
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1 We found that mifepristone could induce a strong interaction between AR and corepressors nuclear receptor corepressor and silencing mediator for retinoid and thyroid hormone receptors in both transactivation and two-hybrid assays to a greater degree than hydroxyflutamide, cyproterone acetate, and bicalutamide. hydroxyflutamide androgen receptor Homo sapiens