Title : BRCT repeats as phosphopeptide-binding modules involved in protein targeting.

Pub. Date : 2003 Oct 24

PMID : 14576432






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These findings provide a molecular basis for BRCT domain function in the DNA damage response and may help to explain why the BRCA1 BRCT domain mutation Met1775 --> Arg, which fails to bind phosphopeptides, predisposes women to breast and ovarian cancer. Arginine BRCA1 DNA repair associated Homo sapiens