Title : N-glucuronidation of nicotine and cotinine by human liver microsomes and heterologously expressed UDP-glucuronosyltransferases.

Pub. Date : 2003 Nov

PMID : 14570768






2 Functional Relationships(s)
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1 Interestingly, when expressed per UGT1A protein, measured by a UGT1A specific antibody, cell lysate from V79-expressed UGT1A9 catalyzed nicotine glucuronidation at a rate 17-fold greater than did UGT1A9 Supersomes. Nicotine UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens
2 Interestingly, when expressed per UGT1A protein, measured by a UGT1A specific antibody, cell lysate from V79-expressed UGT1A9 catalyzed nicotine glucuronidation at a rate 17-fold greater than did UGT1A9 Supersomes. Nicotine UDP glucuronosyltransferase family 1 member A complex locus Homo sapiens