Title : The potential beneficial effect of leptin on an experimental model of hyperlipidemia, induced by chronic ethanol treatment.

Pub. Date : 2003 Nov

PMID : 14568184






3 Functional Relationships(s)
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1 The aim of the present study was to determine the effect of mouse recombinant leptin on food intake, body weight, hepatic and plasma lipids and lipoproteins in alcohol-induced liver injury. Alcohols leptin Mus musculus
2 RESULTS: Exogenous leptin injections to alcohol-fed mice significantly (P<0.05) inhibited the rise in hepatic and plasma lipid and lipoprotein concentrations as compared with those of the unsupplemented ethanol fed mice. Alcohols leptin Mus musculus
3 CONCLUSION: Chronic administration of exogenous mouse recombinant leptin prevents the rise in lipids and lipoprotein concentrations significantly in an animal model of alcohol-induced hyperlipidemia. Alcohols leptin Mus musculus