Title : NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor.

Pub. Date : 2003 Oct

PMID : 14563321






1 Functional Relationships(s)
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1 ART2-catalyzed ADP-ribosylation activates the cytolytic P2X7 purinoceptor, causing calcium flux, pore formation, phosphatidylserine exposure, shedding of CD62L, cell shrinkage, and propidium iodide uptake. Propidium purinergic receptor P2X 7 Homo sapiens