Title : Flavopiridol downregulates the expression of both the inducible NO synthase and p27(kip1) in malignant cells from B-cell chronic lymphocytic leukemia.

Pub. Date : 2003 Dec

PMID : 14523476






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Flavopiridol downregulates the expression of both the inducible NO synthase and p27(kip1) in malignant cells from B-cell chronic lymphocytic leukemia. alvocidib interferon alpha inducible protein 27 Homo sapiens
2 Flavopiridol exposure also results in the stimulation of caspase 3 activity and in caspase-dependent cleavage of p27(kip1), a negative regulator of the cell cycle, which is overexpressed in B-CLL. alvocidib interferon alpha inducible protein 27 Homo sapiens