Title : A conserved catalytic residue in the ubiquitin-conjugating enzyme family.

Pub. Date : 2003 Oct 1

PMID : 14517261






1 Functional Relationships(s)
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1 Here we show that a strictly conserved E2 asparagine residue is critical for catalysis of E2- and E2/RING E3-dependent isopeptide bond formation, but dispensable for upstream and downstream reactions of Ub thiol ester formation. Estradiol cystatin 12, pseudogene Homo sapiens