Pub. Date : 1992 Jul
PMID : 1451028
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Endothelin-1 has been proposed by us as a local mediator for oxygen after demonstrating that it is formed within the ductus and is a potent ductus constrictor. | Oxygen | EDN1 | Ovis aries |
| 2 | We report that release of endothelin-1 from the ductus tends to increase with the oxygen concentration up to a value mimicking the neonatal condition. | Oxygen | EDN1 | Ovis aries |
| 3 | These results implicate endothelin-1 as the effector agent for oxygen in the ductus and, by extension, assign to this peptide a critical role in the closure of the vessel at birth. | Oxygen | EDN1 | Ovis aries |