Pub. Date : 2003 Sep 24
PMID : 14505498
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | BACKGROUND: Kynureninase is a key enzyme on the kynurenine pathway of tryptophan metabolism. | Kynurenine | kynureninase | Homo sapiens |
2 | RESULTS: Two new kynurenine analogues, 3-hydroxydesaminokynurenine and 3-methoxydesaminokynurenine, were synthesised as inhibitors of kynureninase and tested on the tryptophan-induced bacterial enzyme from Pseudomonas fluorescens, the recombinant human enzyme and the rat hepatic enzyme. | Kynurenine | kynureninase | Homo sapiens |