Title : Paradoxical protective effect of aminoguanidine toward low-density lipoprotein oxidation: inhibition of apolipoprotein B fragmentation without preventing its carbonylation. Mechanism of action of aminoguanidine.

Pub. Date : 2003 Sep 30

PMID : 14503886






2 Functional Relationships(s)
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1 Paradoxical protective effect of aminoguanidine toward low-density lipoprotein oxidation: inhibition of apolipoprotein B fragmentation without preventing its carbonylation. pimagedine apolipoprotein B Homo sapiens
2 We hypothesize that, even in the presence of AMG, a nonnegligible proportion of (*)OH radicals remained able to initiate oxidation of the LDL protein moiety, leading to apoB carbonylation. pimagedine apolipoprotein B Homo sapiens