Title : Endothelin-1 modulates hemoglobin-mediated signaling in cerebrovascular smooth muscle via RhoA/Rho kinase and protein kinase C.

Pub. Date : 2004 Jan

PMID : 14500131






1 Functional Relationships(s)
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1 ET-1 (0.1 nM) alone did not produce any significant contraction, but it markedly potentiated the magnitude (223% of control) and rate (149% of control) of contraction in response to OxyHb, which was attenuated by the inhibitors of Rho kinase Y-27632 and HA-1077. histidinoalanine endothelin-1 Oryctolagus cuniculus