Title : Studies on the transferrins of adult serum, cord serum, and cerebrospinal fluid. The effect of neuraminidase.

Pub. Date : 1962 Jan 1

PMID : 14483938






3 Functional Relationships(s)
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1 These components appeared to represent the stepwise removal of the four sialic acid residues from the transferrin molecule, and at large enzyme concentrations, almost all of the transferrin was reduced to the position of the slowest moving component. N-Acetylneuraminic Acid transferrin Homo sapiens
2 These components appeared to represent the stepwise removal of the four sialic acid residues from the transferrin molecule, and at large enzyme concentrations, almost all of the transferrin was reduced to the position of the slowest moving component. N-Acetylneuraminic Acid transferrin Homo sapiens
3 The transferrin pattern of cord blood showed a prominent band in the position of transferrin C, accompanied by four faint slower moving bands which coincided with the four transferrin components produced by the action of neuraminidase on transferrin C. The transferrin pattern of cerebrospinal fluid in individuals homozygous for serum transferrin C showed two principal components, one of which appeared to contain no sialic acid. N-Acetylneuraminic Acid transferrin Homo sapiens