Pub. Date : 1992 May-Jun
PMID : 1427430
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | With these clones we studied the ability of CsA to inhibit TNF and IL-3/GM-CSF production, which was stimulated with specific monoclonal antibodies directed against the CD2 and CD3 surface antigens. | Cyclosporine | CD2 molecule | Homo sapiens |
| 2 | In fact, at 400 ng/ml CsA a residual production of IL-3/GM-CSF was present in all clones tested (CD3: 21.8% and CD2: 14.4% of the maximal IL-3/GM-CSF activity), while secretion of TNF was virtually abrogated at 100 ng/ml. | Cyclosporine | CD2 molecule | Homo sapiens |