Title : Active-site directed irreversible inhibition of diamine oxidase by a homologous series of aziridinylalkylamines.

Pub. Date : 1992 Sep 25

PMID : 1417947






1 Functional Relationships(s)
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1 Three electrophilic homologous aminoalkylaziridine analogues of putrescine, cadaverine, and 1,3-diaminopropane were synthesized and found to represent a mechanistically distinct class of irreversible inhibitors of diamine oxidase. Cadaverine amine oxidase copper containing 1 Homo sapiens