Title : An S1 nuclease-sensitive homopurine/homopyrimidine domain in the PDGF A-chain promoter contains a novel binding site for the growth factor-inducible protein EGR-1.

Pub. Date : 1992 Oct 15

PMID : 1417865






2 Functional Relationships(s)
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1 An S1 nuclease-sensitive homopurine/homopyrimidine domain in the PDGF A-chain promoter contains a novel binding site for the growth factor-inducible protein EGR-1. homopurine early growth response 1 Homo sapiens
2 We now have identified a homopurine/homopyrimidine domain in the promoter region of the PDGF A-chain gene that exhibits S1 nuclease sensitivity in vitro and that contains a novel binding site (5"-TCCTCCTCCTCCTC-3") for the growth factor inducible transcription factor EGR-1 as demonstrated in gel mobility shift assays. homopurine early growth response 1 Homo sapiens