Title : Activation and inhibition of protein kinase C isozymes alpha and beta by Gd3+.

Pub. Date : 1992 Nov 1

PMID : 1416985






2 Functional Relationships(s)
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1 Gd3+ was evaluated as a probe for Ca2+ sites on protein kinase C (PKC) by studying its ability to replace Ca2+ in activation of PKC isozymes II (beta) and III (alpha) in the lipid systems phosphatidylserine/1,2-dioleoyl-sn-glycerol (PS/DO) and diheptanoylphosphatidylcholine (PC7)/DO. 1,2-Dioleoyl-sn-glycerol protein kinase C alpha Homo sapiens
2 Gd3+ was evaluated as a probe for Ca2+ sites on protein kinase C (PKC) by studying its ability to replace Ca2+ in activation of PKC isozymes II (beta) and III (alpha) in the lipid systems phosphatidylserine/1,2-dioleoyl-sn-glycerol (PS/DO) and diheptanoylphosphatidylcholine (PC7)/DO. 1,2-Dioleoyl-sn-glycerol protein kinase C alpha Homo sapiens