Title : Ras controls coupling of growth factor receptors and protein kinase C in the membrane to Raf-1 and B-Raf protein serine kinases in the cytosol.

Pub. Date : 1992 Sep

PMID : 1386920






2 Functional Relationships(s)
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1 We found that mutant Ras blocks serum- and 12-O-tetradecanoyl phorbol 13-acetate-induced activation of Raf-1 kinase in NIH3T3 cells and Raf-1 as well as B-Raf PSK stimulation by nerve growth factor (NGF) in PC12 pheochromocytoma cells. Tetradecanoylphorbol Acetate v-raf-leukemia viral oncogene 1 Mus musculus
2 We found that mutant Ras blocks serum- and 12-O-tetradecanoyl phorbol 13-acetate-induced activation of Raf-1 kinase in NIH3T3 cells and Raf-1 as well as B-Raf PSK stimulation by nerve growth factor (NGF) in PC12 pheochromocytoma cells. Tetradecanoylphorbol Acetate v-raf-leukemia viral oncogene 1 Mus musculus