Title : CD5 acts as a tyrosine kinase substrate within a receptor complex comprising T-cell receptor zeta chain/CD3 and protein-tyrosine kinases p56lck and p59fyn.

Pub. Date : 1992 Oct 1

PMID : 1384049






1 Functional Relationships(s)
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1 Consistent with the formation of a multimeric CD5-TCR zeta/CD3 complex, anti-CD5 crosslinking induced tyrosine phosphorylation of numerous T-cell substrates, similar to those phosphorylated by TCR zeta/CD3 ligation. Tyrosine T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens