Title : Ca(2+)-induced translocation of protein kinase C during Ca(2+)-dependent histamine release from beta-escin-permeabilized rat mast cells.

Pub. Date : 1992

PMID : 1373900






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Ca(2+)-induced translocation of protein kinase C during Ca(2+)-dependent histamine release from beta-escin-permeabilized rat mast cells. Histamine protein kinase C, gamma Rattus norvegicus
2 The apparent Km value of PKC for Ca2+ was 0.33 mumol/l, and this Ca2+ concentration was equivalent to that which can elicit half the maximum of the Ca(2+0-induced histamine release. Histamine protein kinase C, gamma Rattus norvegicus
3 It can be concluded that PKC is translocated into the cell membrane along with an increase in intracellular Ca2+ concentrations and the subsequent activation of PKC may be crucial for the process leading to histamine release. Histamine protein kinase C, gamma Rattus norvegicus
4 It can be concluded that PKC is translocated into the cell membrane along with an increase in intracellular Ca2+ concentrations and the subsequent activation of PKC may be crucial for the process leading to histamine release. Histamine protein kinase C, gamma Rattus norvegicus