Title : Decreased granulocyte-macrophage colony-stimulating factor production by human neonatal blood mononuclear cells and T cells.

Pub. Date : 1992 Mar

PMID : 1373232






1 Functional Relationships(s)
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1 Because granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) play critical roles in the production of neutrophils from marrow precursors, we assessed the ability of leukocytes from neonates and adults to produce GM-CSF, G-CSF, and, for comparison, macrophage colony-stimulating factor (M-CSF) after stimulation with concanavalin A +/- phorbol myristate acetate [blood mononuclear cells (MC) and T lymphocytes] or lipopolysaccharide (monocytes). Tetradecanoylphorbol Acetate colony stimulating factor 3 Homo sapiens