Title : Transcriptional down-regulation of c-myc in human prostate carcinoma cells by the synthetic androgen mibolerone.

Pub. Date : 1992 Mar

PMID : 1373070






2 Functional Relationships(s)
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1 The synthetic androgen mibolerone (7 alpha-17 alpha-Dimethyl-19-nortestosterone) reversibly inhibits the proliferation of LNCaP cells and, from 12-72 h after hormone addition reduces the level of c-myc transcripts to a few per cent of controls. mibolerone MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 The synthetic androgen mibolerone (7 alpha-17 alpha-Dimethyl-19-nortestosterone) reversibly inhibits the proliferation of LNCaP cells and, from 12-72 h after hormone addition reduces the level of c-myc transcripts to a few per cent of controls. mibolerone MYC proto-oncogene, bHLH transcription factor Homo sapiens