Title : Cooperative effects of bombesin, substance P and methacholine on the release of intestinal neurotensin in rats.

Pub. Date : 1992 Jan 23

PMID : 1371613






6 Functional Relationships(s)
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1 Cooperative effects of bombesin, substance P and methacholine on the release of intestinal neurotensin in rats. Methacholine Chloride neurotensin Rattus norvegicus
2 Intraarterial methacholine (MC, 10(-4) M) evoked a prompt and well sustained release of NT in the portal effluent (plateau value at 500% of basal). Methacholine Chloride neurotensin Rattus norvegicus
3 Intraarterial methacholine (MC, 10(-4) M) evoked a prompt and well sustained release of NT in the portal effluent (plateau value at 500% of basal). Methacholine Chloride neurotensin Rattus norvegicus
4 MC potentiated the release of NT induced by B but not that evoked by SP. Methacholine Chloride neurotensin Rattus norvegicus
5 Combined infusion of SP, B and MC produced the largest output of NT. Methacholine Chloride neurotensin Rattus norvegicus
6 In conclusion, B, SP and MC are strong stimulants of NT release in rats. Methacholine Chloride neurotensin Rattus norvegicus