Title : Effect of H2-receptor antagonists on rat liver cytosolic acetyl CoA:arylamine N-acetyltransferase activity.

Pub. Date : 1992 Jan-Feb

PMID : 1371435






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The inhibition of NAT II activity by cimetidine and famotidine was mixed in nature, with characteristics consistent with predominantly competitive inhibitors. Famotidine N-acetyltransferase 1 Rattus norvegicus
2 At an inhibitor:substrate ratio of 2:1, ranitidine, cimetidine, and famotidine reduced NAT II activity by 9, 48, and 75%, respectively. Famotidine N-acetyltransferase 1 Rattus norvegicus