Title : Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides.

Pub. Date : 1992 Mar 1

PMID : 1371302






1 Functional Relationships(s)
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1 N-ras antisense, but not sense, oligodeoxynucleotide treatment of A-T-MNC and CD34+ cells resulted in a significantly decreased number of granulocyte/macrophage colony-forming units (CFU-GM) induced by interleukin 3 (IL-3) or granulocyte/macrophage colony-stimulating factor (GM-CSF) and of macrophage colonies (CFU-M) induced by M-CSF, but not of granulocytic colonies induced with G-CSF or IL-5. Oligodeoxyribonucleotides interleukin 3 Homo sapiens