Title : Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells.

Pub. Date : 2003 Sep 18

PMID : 13679868






2 Functional Relationships(s)
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1 Taken together, these results demonstrate that there are at least two distinct apoptotic pathways: one dependent on O2-, which is induced by 2ME2 and is associated with release of cyto c and Smac; and the other an independent of O2-, which is triggered by Dex and associated with Smac release. Superoxides diablo IAP-binding mitochondrial protein Homo sapiens
2 Taken together, these results demonstrate that there are at least two distinct apoptotic pathways: one dependent on O2-, which is induced by 2ME2 and is associated with release of cyto c and Smac; and the other an independent of O2-, which is triggered by Dex and associated with Smac release. Superoxides diablo IAP-binding mitochondrial protein Homo sapiens