Pub. Date : 2003 Aug
PMID : 13678534
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When STZ-treated animals were posttreated with a derivative of superoxide dismutase that stays in circulation without undergoing renal ultrafiltration, immunoreactivities to MoAb3221 but not to MoAb28131 increased markedly in diabetic retina, suggesting that superoxide cancels free NO for local sGC activation. | Superoxides | guanylate cyclase 1 soluble subunit beta 2 | Rattus norvegicus |
| 2 | These results provide evidence of aberrant utilization of NO and suggest that superoxide plays a role in interfering with NO-mediated sGC activation for phototransducing events in this neural tissue. | Superoxides | guanylate cyclase 1 soluble subunit beta 2 | Rattus norvegicus |