Title : SDZ PSC-833--a novel potent in vitro chemosensitizer in multiple myeloma.

Pub. Date : 1992 Dec

PMID : 1363199






1 Functional Relationships(s)
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1 Drug resistance in the cell line RPMI 8226 dox 40, expressing a high level of Pgp, was almost completely reversed by the novel non-immunosuppressive cyclosporin A (CsA) analog SDZ PSC-833 (PSC), while the chemosensitizers verapamil, CsA and quinine, in clinically achievable concentrations, were much less effective. Quinine phosphoglycolate phosphatase Homo sapiens