Title : Synthesis and pharmacological characterization of 2-(4-chloro-3-hydroxyphenyl)ethylamine and N,N-dialkyl derivatives as dopamine receptor ligands.

Pub. Date : 1992 Nov 13

PMID : 1360027






1 Functional Relationships(s)
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1 The affinity and selectivity of these compounds for D-1 and D-2 subtypes was determined in radioligand competition assays for the DA receptors of rat striatum membranes using [3H]SCH 23390 (D-1 selective) and [3H]spiperone (D-2 selective) as radioligands. Spiperone solute carrier family 3 member 1 Rattus norvegicus