Title : Identification of aspartic acid 514 through glutamic acid 542 as a glycoprotein Ib-IX complex receptor recognition sequence in von Willebrand factor. Mechanism of modulation of von Willebrand factor by ristocetin and botrocetin.

Pub. Date : 1992 Nov 17

PMID : 1359905






2 Functional Relationships(s)
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Protein Name
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1 Mechanism of modulation of von Willebrand factor by ristocetin and botrocetin. Ristocetin von Willebrand factor Bos taurus
2 This peptide inhibited both the ristocetin- and botrocetin-mediated binding of vWF to either platelets or purified GP Ib-IX complex (IC50 approximately 50-200 microM) as well as the asialo-vWF- and bovine vWF-dependent agglutination of platelets. Ristocetin von Willebrand factor Bos taurus