Title : Competitive NMDA receptor antagonists raise electrically kindled generalized seizure thresholds.

Pub. Date : 1992 May

PMID : 1356242






2 Functional Relationships(s)
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1 Two novel, competitive NMDA antagonists, CGP 37849 and CGP 39551, both unsaturated analogues of the NMDA antagonist AP5, showed by far the greatest anticonvulsant potencies (211-fold and 33-fold greater activity than the parent molecule, respectively). N-Methylaspartate adaptor related protein complex 5 subunit beta 1 Homo sapiens
2 Two novel, competitive NMDA antagonists, CGP 37849 and CGP 39551, both unsaturated analogues of the NMDA antagonist AP5, showed by far the greatest anticonvulsant potencies (211-fold and 33-fold greater activity than the parent molecule, respectively). N-Methylaspartate adaptor related protein complex 5 subunit beta 1 Homo sapiens