Pub. Date : 1992 Jun 1
PMID : 1350291
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of adrenaline and isoproterenol, a specific beta-adrenergic agonist, on TNF production were investigated. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 2 | Inhibition of TNF production was observed only if cells were first exposed to adrenaline or isoproterenol at about the same time as to LPS; incubation of THP-1 cells with isoproterenol for 24 h before LPS stimulation dramatically increased response, and prevented suppression of TNF production by a second dose of isoproterenol. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 3 | Inhibition of TNF production was observed only if cells were first exposed to adrenaline or isoproterenol at about the same time as to LPS; incubation of THP-1 cells with isoproterenol for 24 h before LPS stimulation dramatically increased response, and prevented suppression of TNF production by a second dose of isoproterenol. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 4 | Inhibition of TNF production was observed only if cells were first exposed to adrenaline or isoproterenol at about the same time as to LPS; incubation of THP-1 cells with isoproterenol for 24 h before LPS stimulation dramatically increased response, and prevented suppression of TNF production by a second dose of isoproterenol. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 5 | Inhibition of TNF production was observed only if cells were first exposed to adrenaline or isoproterenol at about the same time as to LPS; incubation of THP-1 cells with isoproterenol for 24 h before LPS stimulation dramatically increased response, and prevented suppression of TNF production by a second dose of isoproterenol. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 6 | Inhibition of TNF production was observed only if cells were first exposed to adrenaline or isoproterenol at about the same time as to LPS; incubation of THP-1 cells with isoproterenol for 24 h before LPS stimulation dramatically increased response, and prevented suppression of TNF production by a second dose of isoproterenol. | Isoproterenol | tumor necrosis factor | Homo sapiens |
| 7 | Intracellular cAMP levels were increased by adrenaline and isoproterenol, at concentrations that inhibited TNF production. | Isoproterenol | tumor necrosis factor | Homo sapiens |