Pub. Date : 1992 Nov
PMID : 1331276
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To evaluate the identity of the guanosine triphosphate--binding proteins coupling arginine vasopressin receptor occupancy with activation of phospholipase C, leading to Ca2+ mobilization, and activation of phospholipase A2, leading to arachidonate release and prostanoid formation, we used intact cells, saponin-permeabilized cells, and membranes of the rat mesangial cell. | Arachidonic Acid | arginine vasopressin | Rattus norvegicus |
2 | In contrast arginine vasopressin stimulated arachidonate release from intact mesangial cells, and this effect was blocked by pretreating cells with pertussis toxin. | Arachidonic Acid | arginine vasopressin | Rattus norvegicus |
3 | These data suggest that the release of arachidonic acid by vasopressin in glomerular mesangial cells is linked to a pertussis toxin--sensitive guanosine triphosphate--binding protein and that this activation of phospholipase C in vasopressin is linked to a pertussis toxin--insensitive guanosine triphosphate--binding protein. | Arachidonic Acid | arginine vasopressin | Rattus norvegicus |
4 | These data suggest that the release of arachidonic acid by vasopressin in glomerular mesangial cells is linked to a pertussis toxin--sensitive guanosine triphosphate--binding protein and that this activation of phospholipase C in vasopressin is linked to a pertussis toxin--insensitive guanosine triphosphate--binding protein. | Arachidonic Acid | arginine vasopressin | Rattus norvegicus |