Title : Azatyrosine inhibits neurite outgrowth of PC12 cells induced by oncogenic Ras.

Pub. Date : 1992 Oct

PMID : 1328988






2 Functional Relationships(s)
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1 An antibiotic, azatyrosine [L-beta-(5-hydroxy-2-pyridyl) alanine], specifically converts ras-, raf- or c-erbB2 (neu)-transformed NIH3T3 cells to apparently normal phenotype. beta-(5-hydroxy-2-pyridyl)alanine zinc fingers and homeoboxes 2 Mus musculus
2 In the present study, we found that neurite outgrowth of PC12 cells induced by expression of either the ras or raf oncogenes was inhibited by addition of azatyrosine to the medium. beta-(5-hydroxy-2-pyridyl)alanine zinc fingers and homeoboxes 2 Mus musculus