Title : The effects of cyclic imides on lipoprotein receptor binding and degradation of rat and human cells and effects on regulatory enzymes of lipid metabolism.

Pub. Date : 1992 Apr

PMID : 1325661






1 Functional Relationships(s)
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1 A series of cyclic imides, which possess a bulkier N-ring structure than phthalimide and saccharin, were shown to suppress LDL receptor binding, internalization and degradation of isolated rat hepatocytes, foam cells, human fibroblasts and mouse macrophages. Saccharin low density lipoprotein receptor Rattus norvegicus