Title : Product analyses in DNA strand scission by antitumor antibiotic elsamicin A.

Pub. Date : 1992 Jul 15

PMID : 1321617






1 Functional Relationships(s)
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1 The results lead to the conclusion that the hydroxyl radical formed in Fe(II)-elsamicin A plus dithiothreitol system oxidizes the deoxyribose moiety via hydrogen abstraction predominantly at the C-4" carbon of the deoxyribose backbone and ultimately produces strand breakage of DNA. Carbon complement C4A (Rodgers blood group) Homo sapiens