Title : Structural basis for modulation and agonist specificity of HCN pacemaker channels.

Pub. Date : 2003 Sep 11

PMID : 12968185






1 Functional Relationships(s)
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1 Here we have investigated the mechanism underlying this modulation by studying a carboxy-terminal fragment of HCN2 containing the cyclic nucleotide-binding domain (CNBD) and the C-linker region that connects the CNBD to the pore. Nucleotides, Cyclic hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 Homo sapiens