Title : Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D.

Pub. Date : 2003 Sep 15

PMID : 12963694






1 Functional Relationships(s)
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1 Here, we report that the serine protease plasmin cleaved both propeptides from the VEGF homology domain of human VEGF-D and thereby generated a mature form exhibiting greatly enhanced binding and cross-linking of VEGFR-2 and VEGFR-3 in comparison to full-length material. propeptides vascular endothelial growth factor D Homo sapiens