Pub. Date : 2003 Oct
PMID : 12958025
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rac regulates cardiovascular superoxide through diverse molecular interactions: more than a binary GTP switch. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Rac has two major functions: 1) it regulates the organization of the actin cytoskeleton, and 2) it controls the activity of the key enzyme complex NADPH oxidase to control superoxide production in both phagocytes and nonphagocytic cells. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | In phagocytes, superoxide derived from NADPH has a bactericidal function, whereas Rac-derived superoxide in the cardiovascular system has a diverse array of functions that have recently been a subject of intense interest. | Superoxides | AKT serine/threonine kinase 1 | Homo sapiens |